kaberett: Grinning emoticon. (:D)
[personal profile] kaberett

Realisation while wrangling laundry, presented as a series of facts:

  • I have both migraine and endometriosis
  • migraine means that I am limited to 6 days (or 8 if I push it and am willing to stare down my migraine team) of painkillers (which includes paracetamol, NSAIDs and codeine, as well as triptans) per month
  • a thing that Mostly works to head off incipient breakthrough migraines is The Frovatriptan Protocol, which consists of frovatriptan + mefenamic acid (an NSAID) + paracetamol (optionally) + (in my case) prochlorperazine (definitely)
    • each time I use The Frovatriptan Protocol I use up one (1) of my Six (6) Days Per Month
  • migraine is. not. my only source of chronic pain.
  • but I'd rather deal with endometriosis- and joint- etc etc etc-related pain than migraine fuckery, so I am currently significantly undermedicating my non-migraine pain
  • BUT
  • ON THE 14TH OF SEPTEMBER, NICE APPROVED RIMEGEPANT FOR ACUTE USE
    • rimegepant, as the name suggests, is not a triptan -- it is a gepant
    • this is a class of drug that works on the same basis as the stabs I'm currently using and responding generally pretty well to -- it targets CGRP signalling/pathways/thingy
    • crucially, it has been conclusively demonstrated in clinical trials that this medication DOES NOT contribute to so-called medication overuse headache, so taking rimegepant does not count toward the six-day budget
  • my next headache clinic appointment is on the 18th of December
  • which is more than 3 months after the NICE approval was issued
  • so I will theoretically be able to switch from The Frovatriptan Protocol to rimegepant, thereby freeing up all my six-day painkiller budget for managing non-migraine pain

AT WHICH POINT I might even be happy cancelling my pain clinic referral? We'll see.

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kaberett

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